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News from the Gurdon Institute

27.04.17 Winners of our Zoom Box photo competition announced

Images taken with Zoom Boxes assembled at our Science Festival event have now been judged and prizes are on their way

27.04.17 Winners of our Zoom Box photo competition announced - Read More…

21.03.17 Surani lab show role for maternally inherited protein, Stella

21.03.17 Surani lab show role for maternally inherited protein, Stella

In this eLife paper, the Surani lab with EMBL colleagues show that Stella controls activation of transposable elements in the developing embryo

21.03.17 Surani lab show role for maternally inherited protein, Stella - Read More…

27.03.17 Rawlins and Piddini lab pinpoint role of FGFR2 in adult airway homeostasis

27.03.17 Rawlins and Piddini lab pinpoint role of FGFR2 in adult airway homeostasis

In this Development article, two collaborating research groups at the Gurdon Institute show that signalling through FGF receptor 2 is required for airway homeostasis

27.03.17 Rawlins and Piddini lab pinpoint role of FGFR2 in adult airway homeostasis - Read More…

30.03.17 Epigenetic memory of somatic cell identity inhibits reprogramming in nuclear transfer

30.03.17 Epigenetic memory of somatic cell identity inhibits reprogramming in nuclear transfer

The Gurdon lab show that genes retain a memory of their identity and active state that underlies resistance to reprogramming in nuclear transfer

30.03.17 Epigenetic memory of somatic cell identity inhibits reprogramming in nuclear transfer - Read More…

02.03.17 Identifying genes resistant to reprogramming and how epigenetic pathways are involved

02.03.17 Identifying genes resistant to reprogramming and how epigenetic pathways are involved

Performing nuclear transfer of mouse ES cells and fibroblasts allowed the Gurdon lab with international colleagues to identify genes that resist reprogramming

02.03.17 Identifying genes resistant to reprogramming and how epigenetic pathways are involved - Read More…

30.01.17 Surani lab with Institut Curie colleagues probe Xist-mediated gene silencing in early embryogenesis

30.01.17 Surani lab with Institut Curie colleagues probe Xist-mediated gene silencing in early embryogenesis

Analysing Xist-mutant embryos down to single-cell RNA sequencing, the Surani and Heard (Institut Curie) labs examine the epigenetic process of X-chromosome inactivation

30.01.17 Surani lab with Institut Curie colleagues probe Xist-mediated gene silencing in early embryogenesis - Read More…

25.10.16 Synthetic-lethal combination of PAXX and XLF loss in mammalian development

25.10.16 Synthetic-lethal combination of PAXX and XLF loss in mammalian development

In this Genes & Development paper, the Jackson group and colleagues demonstrate the combined lethality of PAXX and XLF gene knockouts

25.10.16 Synthetic-lethal combination of PAXX and XLF loss in mammalian development - Read More…

13.11.16  Meri Huch wins Hamdan Award for Medical Research Excellence 2015-2016

13.11.16 Meri Huch wins Hamdan Award for Medical Research Excellence 2015-2016

Gurdon Institute Group Leader Meri Huch has won a prestigious prize from the Dubai-based Sheikh Hamdan bin Rashid al Maktoum Award for Medical Sciences

13.11.16 Meri Huch wins Hamdan Award for Medical Research Excellence 2015-2016 - Read More…

31.10.16 Jackson group demonstrate how haploid ES cells can provide new genetic screening platform

31.10.16 Jackson group demonstrate how haploid ES cells can provide new genetic screening platform

This Nature Chemical Biology publication from Steve Jackson's group reveals a genetic screening platform based on haploid embryonic stem cells

31.10.16 Jackson group demonstrate how haploid ES cells can provide new genetic screening platform - Read More…

25.10.16 Ahringer lab study of chromatin domains finds separation of genes with different functions

25.10.16 Ahringer lab study of chromatin domains finds separation of genes with different functions

This PNAS paper shows that the higher-order structure of chromatin exhibits domains separating broadly-expressed genes from those that are developmentally regulated

25.10.16 Ahringer lab study of chromatin domains finds separation of genes with different functions - Read More…

18.10.16 Emma Rawlins' group shows that extrinsic signals drive lung epithelial cell fate

18.10.16 Emma Rawlins' group shows that extrinsic signals drive lung epithelial cell fate

In this Development paper, the Rawlins group with colleagues in Edinburgh investigate the mechanisms controlling the fate of developing lung epithelial cells

18.10.16 Emma Rawlins' group shows that extrinsic signals drive lung epithelial cell fate - Read More…

06.09.16 Andrea Brand awarded Royal Society Darwin Professorship

06.09.16 Andrea Brand awarded Royal Society Darwin Professorship

The Royal Society announced today that the Gurdon Institute's Andrea Brand is one of six world-class scientists to whom they have awarded prestigious Research Professorships

06.09.16 Andrea Brand awarded Royal Society Darwin Professorship - Read More…

07.07.16 Gurdon Institute scientists reveal ultra-high resolution 3D imaging of "virtually any subcellular structure"

07.07.16 Gurdon Institute scientists reveal ultra-high resolution 3D imaging of "virtually any subcellular structure"

The culmination of a decade's research on high-resolution fluorescence imaging techniques, resulting in a dramatically increased imaging depth combined with nanoscale resolution, is presented in new Cell paper

07.07.16 Gurdon Institute scientists reveal ultra-high resolution 3D imaging of "virtually any subcellular structure" - Read More…

08.07.16 Simons lab publish findings on the cell of origin in basal cell carcinoma

08.07.16 Simons lab publish findings on the cell of origin in basal cell carcinoma

In a new Nature paper, Ben Simons and colleagues combine mathematical modelling with the study of cancer biology, proving that basal cell carcinomas arise specifically from stem cells

08.07.16 Simons lab publish findings on the cell of origin in basal cell carcinoma - Read More…

29.06.16 Watching individual cancer cells dividing and squeezing through nanotubes

29.06.16 Watching individual cancer cells dividing and squeezing through nanotubes

Jackson group postdoc Christine Schmidt's new paper in ACS Nano shows how cancer cells behave in see-through nanotubes designed to mimic blood capillaries

29.06.16 Watching individual cancer cells dividing and squeezing through nanotubes - Read More…

16.06.16 New model for stem cell self-renewal emphasises reversible states

16.06.16 New model for stem cell self-renewal emphasises reversible states

Ben Simons and Philip Greulich show that a model in which stem cells exhibit ‘dynamic heterogeneity’ can robustly explain patterns of self-renewal and differentiation, contributing to our understanding of tissue maintenance.

16.06.16 New model for stem cell self-renewal emphasises reversible states - Read More…