miska laboratorypublications

2012
Castro C, Sar F, Shaw FR, Mishima M, Miska EA, Griffin JL, (2012) A metabolomic strategy defines the regulation of lipid content and global metabolism by Delta-9 desaturases in Caenorhabditis elegans. BMC Genomics doi:10.1186/1471-2164-13-36

Marie-Laure Baudet, Krishna H Zivraj, Cei Abreu-Goodger, Alistair Muldal, Javier Armisen, Cherie Blenkiron, Leonard D Goldstein, Eric A Miska & Christine E Holt. (2012) miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones. Nature Neuroscience 15, 29–38

2011
Lightfoot HL, Bugaut A, Armisen Garrido J, Lehrbach NJ, Miska EA, Balasubramanian SA (2011) LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing. Biochemistry 50, 7514–7521 .

Félix MA, Ashe A, Piffaretti J, Wu G, Nuez I, Bélicard T, Jiang Y, Zhao G, Franz CJ, Goldstein LD, Sanroman M, Miska EA, Wang D.(2011) Natural and experimental infection of Caenorhabditis nematodes by novel viruses related to nodaviruses. PLoS Biol. Jan 25;9(1):e1000586.

2010
Lehrbach NJ and Miska EA (2010) in Regulation of microRNAs, Helge Grosshans Ed., Landes Bioscience, ISBN: 978-1-4419-7822-6

Jovanovic M, Reiter L, Picotti P, Lange V, Bogan E, Hurschler BA, Blenkiron C, Lehrbach NJ, Ding XC, Weiss M, Schrimpf SP, Miska EA, Grosshans H, Aebersold R and Hengartner MO (2010) A quantitative targeted proteomics approach to validate predicted micrornA targets in C. elegans. Nature Methods, in press.

Hanina SA, Mifsud W, Down TD, Hayashi K, O’Carroll D, Lao K, Miska EA and Surani MA (2010) Genome-wide Identification of Targets & Function of Individual MicroRNAs in Mouse Embryonic Stem Cells. PLoS Genetics, in press.

Kaufman E and Miska EA (2010) The microRNAs of Caenorhabditis elegans. Seminars in Cell and Dev Biol, 21, 728–737.

Shaw WR, Armisen J, Lehrbach NJ and Miska EA (2010) The conserved miR-51 microRNA family regulates cell adhesion and the Fat cadherin ortholog CDH-3 in Caenorhabditis elegans Genetics, 185, 897-905.

Clark AM, Goldstein LD, Tevlin M, Tavare S, Shaham S and Miska EA (2010) The microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans. NAR, 38, 3780–3793

Avril-Sassen S*, Goldstein LD*, Stingl J, Blenkiron C, Le Quesne J, Spiteri I, Karagavriilidou K, Watson CJ, Tavaré S, Miska EA*, Caldas C* (2009) Characterisation of microRNA expression in post-natal mouse mammary gland development. BMC Genomics 2009 Nov 20;10:548 (*equal contribution)

2009
Lehrbach N, Armisen J, Lightfoot H, Murfitt K, Bugaut A, Balasubramanian S, Miska EA (2009) LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans. Nat Struct Mol Biol 10, 1016-20

Armisen J, Gilchrist MJ, Wilczynska A, Standart N and Miska EA (2009) Abundant and dynamically expressed miRNAs, endo-siRNAs and piRNAs in the African clawed frog Xenopus tropicalis. Genome Research 10, 1766-75

Wilczynska A, Minshall N, Armisen J, Miska EA, Standart N (2009) Two Piwi proteins, Xiwi and Xili, are expressed in the Xenopus female germline. RNA 15, 337-345

2008
Lykke-Andersen K, Gilchrist MJ, Grabarek JB, Das P, Miska E, Zernicka-Goetz M (2008) Maternal Argonaute 2 Is Essential for Early Mouse Development at the Maternal-Zygotic Transition. Mol Biol Cell 19, 4383-4392

Das PP, Bagijn MP, Goldstein LD, Woolford JR, Lehrbach NJ, Sapetschnig A, Buhecha HR, Gilchrist MJ, Howe KJ, Stark R, Berezikov E, Ketting RF, Tavaré S, Miska EA (2008) Piwi and piRNAs Act Upstream of an Endogenous siRNA Pathway to suppress Tc3 Transposon Mobility in the Caenorhabditis elegans germline. Mol Cell 31, 79-90

Lehrbach NJ, Miska EA (2008) Functional genomic, computational and proteomic analysis of C. elegans microRNAs. Brief Funct Genomic Proteomic 7, 228-235

Miska EA (2008) MicroRNAs--keeping cells in formation. Nat Cell Biol 10, 501-502

Atherton HJ, Jones OA, Malik S, Miska EA, Griffin JL (2008) A comparative metabolomic study of NHR-49 in Caenorhabditis elegans and PPAR-alpha in the mouse. FEBS Lett 582, 1661-6

Hayashi K, Chuva de Sousa Lopes SM, Kaneda M, Tang F, Hajkova P, Lao K, O'Carroll D, Das PP, Tarakhovsky A, Miska EA, Surani MA (2008) MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis. PLoS ONE 3, 1738

Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C. (2008) Members of the miRNA-200 Family Regulate Olfactory Neurogenesis. Neuron 57, 41-55

Sassen S, Miska EA, Caldas C (2008) MicroRNA - implications for cancer. Virchows Arch. 452, 1-10

2007
Vigorito E, Perks KL, Abreu-Goodger C, Bunting S, Xiang Z, Kohlhaas S, Das PP, Miska EA, Rodriguez A, Bradley A, Smith KG, Rada C, Enright AJ, Toellner KM, Maclennan IC, Turner M. (2007) microRNA-155 Regulates the Generation of Immunoglobulin Class-Switched Plasma Cells. Immunity 27, 847-59

Blenkiron C*, Goldstein LD*, Thorne NP, Spiteri I, Chin SF, Dunning M, Barbosa-Morais NL, Teschendorff A, Green AR, Ellis IO, Tavaré S, Caldas C, Miska EA (2007) MicroRNA expression profiling of human breast cancer identifies new markers of tumour subtype. Genome Biology 8, R214 (* equal contribution)

Miska EA*, Alvarez-Saavedra A*, Abbott AL*, Lau NC, Hellman A, McGonagle SM, Bartel DP, Ambros VR, Horvitz HR (2007) The biological roles of microRNAs in Caenorhabditis elegans. PLoS Genetics 12, e215 (* equal contribution)

Miska EA (2007) The expanding world of small RNA: from germ cells to cancer. European Pharmaceutical Review 5, 34-37

O'Carroll D, Mecklenbrauker I, Das PP, Santana A, Koenig U, Enright AJ, Miska EA, Tarakhovsky A (2007) A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway. Genes Dev 21, 1999-2004

Blenkiron C, Miska EA, (2007) miRNAs in cancer: approaches, aetiology, diagnostics and therapy. Hum Mol Genet 16, R106-113

Rodriguez A, Vigorito E, Clare S, Warren MV, Couttet P, Soond DR, van Dongen S, Grocock RJ, Das PP, Miska EA, Vetrie D, Okkenhaug K, Enright AJ, Dougan G, Turner M, Bradley A (2007) Requirement of bic/microRNA-155 for normal immune function. Science 316, 608-611

Alvarez-Garcia I, Miska EA (2007) MiRNA expression analysis in C. elegans and mammals by microarrays. In: microRNAs: from basic science to disease biology. Appasani K (ed.) Cambridge University Press, ISBN 978-0-521-86598-2

Miska EA, Ahringer J (2007) RNA interference has second helpings. Nature Biotechnology 25, 302-303

Lujambio A, Ropero S, Ballestar E, Fraga MF, Cerrato C, Setien F, Casado S, Suarez-Gauthier A, Sanchez-Cespedes M, Gitt A, Spiteri I, Das PP, Caldas C, Miska EA, Esteller M (2007) Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res. 67, 1424-1429

2006
Miska EA (2006) Functional Roles of RNAi in C. elegans In: RNA Interference: Principles and Applications. Henry Stewart Talks Series

2005
Alvarez-Saavedra EA, Miska EA (2005) Caenorhabditis elegans and friends in Los Angeles. Genome Biology 6, 358

Alvarez-Garcia I, Miska EA (2005) MicroRNA functions in animal development and human disease. Development 132, 4653-4662

Abbott AL*, Alvarez-Saavedra E*, Miska EA*, Lau NC, Bartel DP, Horvitz HR, Ambros V (2005) The let-7 MicroRNA Family Members mir-48, mir-84, and mir-241 Function Together to Regulate Developmental Timing in Caenorhabditis elegans. Dev Cell 9, 403-414 (* equal contribution)

Miska EA (2005) How microRNAs control cell division, differentiation and death. Curr Opin Genet Dev 15, 563-568

Lu J*, Getz G*, Miska EA*, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, Horvitz HR, Golub TR (2005) MicroRNA expression profiles classify human cancers. Nature 435, 834 (* equal contribution)

Wienholds E, Kloosterman WP, Miska EA, Alvarez-Saavedra E, Berezikov E, de Bruijn E, Horvitz RH, Kauppinen S, Plasterk RH (2005) MicroRNA Expression in Zebrafish Embryonic Development. Science 309, 310

2004
Miska EA*, Alvarez-Saavedra A*, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR (2004) Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biology 5, R60.(* equal contribution)

2002
Kirsh O, Seeler JS, Pichler A, Gast A, Muller S, Miska EA, Mathieu M, Harel-Bellan A, Kouzarides T, Melchior F, Dejean A. (2002) The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase. EMBO J 21, 2682.

Wolf D, Rodova M, Miska EA, Calvet JP, Kouzarides T. (2002) Acetylation of beta-catenin by CREB-binding protein (CBP). J Biol Chem 277, 25562.

2001
Miska EA, Brehm A. (2001) Remodelling chromatin in worms. ELSO Gazette 5

Miska EA, Langley E, Wolf D, Karlsson C, Pines J, Kouzarides T. (2001) Differential localization of HDAC4 orchestrates muscle differentiation. NAR. 29, 3439

Bannister AJ, Zegerman P, Partridge JF, Miska EA, Thomas JO, Allshire RC, Kouzarides T. (2001) Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410, 120

2000
Bannister AJ, Miska EA. (2000) Regulation of gene expression by transcription factor acetylation. Cell Mol Life Sci. 57, 1184

Bannister AJ, Miska EA, Gorlich D, Kouzarides T. (2000) Acetylation of importin-alpha nuclear import factors by CBP/p300. Curr Biol. 10, 467

Grimes JA, Nielsen SJ, Battaglioli E, Miska EA, Speh JC, Berry DL, Atouf F, Holdener BC, Mandel G, Kouzarides T. (2000) The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex. J Biol Chem. 275, 9461

Huang EY, Zhang J, Miska EA, Guenther MG, Kouzarides T, Lazar MA. (2000) Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway. Genes Dev. 29, 3439

1999
Miska EA, Karlsson C, Langley E, Nielsen SJ, Pines J, Kouzarides T. (1999) HDAC4 deacetylase associates with and represses the MEF2 transcription factor. EMBO J 18, 5099

Sparrow DB, Miska EA, Langley E, Reynaud-Deonauth S, Kotecha S, Towers N, Spohr G, Kouzarides T, Mohun TJ. (1999) Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. EMBO J. 18, 5085

Brehm A, Miska EA, Reid J, Bannister A, Kouzarides T. (1999) The cell cycle-regulating transcription factors E2F-RB. Br J Cancer. 80(Supl.), 38

Miska EA*, Brehm A*, Nielsen SJ*, McCance DJ, Reid JL, Bannister AJ, Kouzarides T. (1999) The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth. EMBO J. 18, 2449 (* equal contribution)

1998
Brehm A, Miska EA, McCance DJ, Reid JL, Bannister AJ, Kouzarides T. (1998) Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature 391, 597