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Research Directory

    Studying development to understand disease

    The Gurdon Institute is funded by Wellcome and Cancer Research UK to study the biology of development, and how normal growth and maintenance go wrong in cancer and other diseases.

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    Integrin signaling downregulates filopodia in muscle-tendon attachment

    Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development

    DDX3X RNA helicase affects breast cancer cell cycle progression by regulating expression of KLF4

    Natural Genetic Variation in a Multigenerational Phenotype in C. elegans

    On the origin of the human germline

    Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells 

    Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency

    Immune Cell Dynamics Unfolded by Single-Cell Technologies

    Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes

    Integrin α2 marks a niche of trophoblast progenitor cells in first trimester human placenta

    Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway

    SLAM-ITseq: Sequencing cell type-specific transcriptomes without cell sorting

    SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements

    scmap: projection of single-cell RNA-seq data across data sets

    Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis

    Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48

    The developmental origin of brain tumours: a cellular and molecular framework

     

     

    Link to full list on PubMed