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Research Directory

    Studying development to understand disease

    The Gurdon Institute is funded by Wellcome and Cancer Research UK to study the biology of development, and how normal growth and maintenance go wrong in cancer and other diseases.

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    Immune Cell Dynamics Unfolded by Single-Cell Technologies

    Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes

    Integrin α2 marks a niche of trophoblast progenitor cells in first trimester human placenta

    Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway

    SLAM-ITseq: Sequencing cell type-specific transcriptomes without cell sorting

    SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements

    scmap: projection of single-cell RNA-seq data across data sets

    Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis

    Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48

    The developmental origin of brain tumours: a cellular and molecular framework

    Bioinformatics challenges and perspectives when studying the effect of epigenetic modifications on alternative splicing

    ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

    Extracellular Forms of Aβ and Tau from iPSC Models of Alzheimer's Disease Disrupt Synaptic Plasticity

    Combinational Treatment of Trichostatin A and Vitamin C Improves the Efficiency of Cloning Mice by Somatic Cell Nuclear Transfer

    Predominant Asymmetrical Stem Cell Fate Outcome Limits the Rate of Niche Succession in Human Colonic Crypts

    G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst

    Link to full list on PubMed