Current Prospectus: 2019 — The Gurdon Institute

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Institute reopening

The Gurdon Institute reopened on Monday 15th June. Many staff will continue to work from home, and all staff may be contacted by email.

Studying development to understand disease

The Gurdon Institute is funded by Wellcome and Cancer Research UK to study the biology of development, and how normal growth and maintenance go wrong in cancer and other diseases.

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Our recent publications

Behavior and lineage progression of neural progenitors in the mammalian cortex

The short and long-range RNA-RNA Interactome of SARS-CoV-2

Distinctive regulatory architectures of germline-active and somatic genes in C. elegans

SID-2 negatively regulates development likely independent of nutritional dsRNA uptake

Involvement of circulating factors in the transmission of paternal experiences through the germline

Tracing the cellular basis of islet specification in mouse pancreas

TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control

Injected cells provide a valuable complement to cell-free systems for analysis of gene expression

Trajectory and uniqueness of mutational signatures in yeast mutators

The phosphoinositide 3-kinase inhibitor alpelisib restores actin organization and improves proximal tubule dysfunction in vitro and in a mouse model of Lowe syndrome and Dent disease

Link to full list on PubMed