Current Prospectus: 2019 — The Gurdon Institute

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Institute reopening

The Gurdon Institute reopened on Monday 15th June. Many staff will continue to work from home, and all staff may be contacted by email.

Studying development to understand disease

The Gurdon Institute is funded by Wellcome and Cancer Research UK to study the biology of development, and how normal growth and maintenance go wrong in cancer and other diseases.

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Our recent publications

The phosphoinositide 3-kinase inhibitor alpelisib restores actin organization and improves proximal tubule dysfunction in vitro and in a mouse model of Lowe syndrome and Dent disease

KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements

Mechanisms of stretch-mediated skin expansion at single-cell resolution

Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription

Distal lung epithelial progenitor cell function declines with age

Widespread Conservation and Lineage-Specific Diversification of Genome-Wide DNA Methylation Patterns Across Arthropods

Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machine

Long-term association of a transcription factor with its chromatin binding site can stabilize gene expression and cell fate commitment

High-Throughput Quantitative RT-PCR in Single and Bulk C. elegans Samples Using Nanofluidic Technology

Variable Outcomes in Neural Differentiation of Human PSCs Arise from Intrinsic Differences in Developmental Signaling Pathways

Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

Long-term association of a transcription factor with its chromatin binding site can stabilize gene expression and cell fate commitment

Link to full list on PubMed