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20.07.15 Ben Simons awarded Royal Society’s Gabor Medal 2015

last modified Jul 20, 2015 11:20 AM
Interdisciplinary research by Professor Ben Simons of the Gurdon Institute and the Cavendish Laboratory is recognised by award of Gabor Medal from Royal Society
20.07.15 Ben Simons awarded Royal Society’s Gabor Medal 2015

Professor Benjamin D Simons

Professor Ben Simons, Affiliated Group Leader at the Wellcome Trust/ Cancer Research UK Gurdon Institute in Cambridge, has been awarded the Royal Society’s Gabor Medal 2015, in recognition of his “work analysing stem cell lineages in development, tissue homeostasis and cancer, revolutionising our understanding of stem cell behaviour in vivo”.

The Gabor Medal specifically recognises distinction in “interdisciplinary work between the life sciences with other disciplines”.  Professor Simons spent twenty years as a theoretical physicist before taking up a biological quest to understand how mammalian tissues are maintained by cell renewal.  Studies of cell turnover and lineage tracing can generate very large datasets, to which Simons applies data analysis techniques from physics to tease out previously unknown properties of stem cell populations. This work has advanced our understanding of how tissues are maintained in both health and disease.

Simons splits his time between the Gurdon Institute and the Cavendish Laboratory of the Department of Physics where he holds the Herchel Smith Chair.

The Gurdon Institute is also home to a previous winner of the Gabor Medal, Professor Azim Surani, who was awarded the medal in 2001 in recognition of his discovery of mammalian genomic imprinting.

The Gabor Medal was created in memory of the engineer Dennis Gabor FRS (1900-1979). The first award was made in 1989. The medal is silver gilt and is accompanied by a gift of £2000. 

 

Studying development to understand disease

The Gurdon Institute is funded by Wellcome and Cancer Research UK to study the biology of development, and how normal growth and maintenance go wrong in cancer and other diseases.

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Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells

Disease modelling in human organoids

The role of integrins in Drosophila egg chamber morphogenesis

Tracing the cellular dynamics of sebaceous gland development in normal and perturbed states

Neural stem cell dynamics: the development of brain tumours

Liver organoids: from basic research to therapeutic applications

NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs

The roles of DNA, RNA and histone methylation in ageing and cancer

Separating Golgi proteins from cis to trans reveals underlying properties of cisternal localization

Sequencing cell-type-specific transcriptomes with SLAM-ITseq

Mature sperm small-RNA profile in the sparrow: implications for transgenerational effects of age on fitness

Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction

Derivation and maintenance of mouse haploid embryonic stem cells

Establishment of porcine and human expanded potential stem cells

Adapting machine-learning algorithms to design gene circuits

Lgr5+ stem/progenitor cells reside at the apex of a heterogeneous embryonic hepatoblast pool

Identification of a regeneration-organizing cell in the Xenopus tail

Citrullination of HP1γ chromodomain affects association with chromatin

A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons

A transmissible RNA pathway in honey bees

METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation 

Link to full list on PubMed