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14.03.18 Invitation to a special seminar by Julie Ahringer, Gurdon Institute

last modified Mar 14, 2018 01:21 PM
Join us to hear Julie Ahringer, Professor of Genetics and Genomics at the Gurdon Institute, describe her research on in vivo mechanisms that control chromatin architecture and gene expression in development

Ahringer special seminar

Abstract: Regulation of the genome takes place in the context of chromatin, the organisation of DNA with histones and hundreds of associated proteins and RNAs. Although the sequence of DNA is essentially the same in all cells, chromatin structure differs at local and domain-scale levels to achieve correct patterns of active and repressed transcription. This regulation of chromatin structure plays a central role in normal development and its misregulation is associated with disease. I will discuss our work using the animal model C. elegans to determine in vivo mechanisms that control chromatin architecture and gene expression in development.

Studying development to understand disease

The Gurdon Institute is funded by Wellcome and Cancer Research UK to study the biology of development, and how normal growth and maintenance go wrong in cancer and other diseases.

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