skip to primary navigationskip to content

14.03.18 Invitation to a special seminar by Julie Ahringer, Gurdon Institute

last modified Mar 14, 2018 01:21 PM
Join us to hear Julie Ahringer, Professor of Genetics and Genomics at the Gurdon Institute, describe her research on in vivo mechanisms that control chromatin architecture and gene expression in development

Ahringer special seminar

Abstract: Regulation of the genome takes place in the context of chromatin, the organisation of DNA with histones and hundreds of associated proteins and RNAs. Although the sequence of DNA is essentially the same in all cells, chromatin structure differs at local and domain-scale levels to achieve correct patterns of active and repressed transcription. This regulation of chromatin structure plays a central role in normal development and its misregulation is associated with disease. I will discuss our work using the animal model C. elegans to determine in vivo mechanisms that control chromatin architecture and gene expression in development.

Studying development to understand disease

The Gurdon Institute is funded by Wellcome and Cancer Research UK to study the biology of development, and how normal growth and maintenance go wrong in cancer and other diseases.

combinedLogo x3 trans2018


Share this

Immune Cell Dynamics Unfolded by Single-Cell Technologies

Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes

Integrin α2 marks a niche of trophoblast progenitor cells in first trimester human placenta

Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway

SLAM-ITseq: Sequencing cell type-specific transcriptomes without cell sorting

SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements

scmap: projection of single-cell RNA-seq data across data sets

Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis

Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48

The developmental origin of brain tumours: a cellular and molecular framework

Bioinformatics challenges and perspectives when studying the effect of epigenetic modifications on alternative splicing

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

Extracellular Forms of Aβ and Tau from iPSC Models of Alzheimer's Disease Disrupt Synaptic Plasticity

Combinational Treatment of Trichostatin A and Vitamin C Improves the Efficiency of Cloning Mice by Somatic Cell Nuclear Transfer

Predominant Asymmetrical Stem Cell Fate Outcome Limits the Rate of Niche Succession in Human Colonic Crypts

G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst

Link to full list on PubMed