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TEMPORARY CLOSURE

The Gurdon Institute closed on Friday 20th March for all but essential activities in order to protect staff from the COVID-19 outbreak.

We can still be contacted by email.

Studying development to understand disease

The Gurdon Institute is funded by Wellcome and Cancer Research UK to study the biology of development, and how normal growth and maintenance go wrong in cancer and other diseases.

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Tweets by @GurdonInstitute

Our recent publications

Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection

A direct role for SNX9 in the biogenesis of filopodia

A dot-stripe Turing model of joint patterning in the tetrapod limb

A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons

Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids

Tissue-specific profiling reveals distinctive regulatory architectures for ubiquitous, germline and somatic genes

Tailless/TLX reverts intermediate neural progenitors to stem cells driving tumourigenesis via repression of asense/ASCL1

On growth and force: mechanical forces in development

Chronic irradiation of human cells reduces histone levels and deregulates gene expression

PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1

Activin A and BMP4 Signaling Expands Potency of Mouse Embryonic Stem Cells in Serum-Free Media

The myeloid lineage is required for the emergence of a regeneration permissive environment following Xenopus tail amputation

Filopodia and their links with membrane traffic and cell adhesion

Ancestral Hybridisation Facilitated Species Diversification in the Lake Malawi Cichlid Fish Adaptive Radiation

Link to full list on PubMed