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We are recruiting GLx1

Studying development to understand disease

The Gurdon Institute is funded by Wellcome and Cancer Research UK to study the biology of development, and how normal growth and maintenance go wrong in cancer and other diseases.

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MDC1 PST-repeat region promotes histone H2AX-independent chromatin association and DNA damage tolerance

Checkpoint inhibition of origin firing prevents DNA topological stress

Small Molecule Inhibition of UBE2T/FANCL-mediated Ubiquitylation in the Fanconi Anemia Pathway

Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration

Neurogenin3 phosphorylation controls reprogramming efficiency of pancreatic ductal organoids into endocrine cells

Mutations in thyroid hormone receptor α1 cause premature neurogenesis and progenitor cell depletion in human cortical development

Neural stem cell temporal patterning and brain tumour growth rely on oxidative phosphorylation

Testing the role of SOX15 in human primordial germ cell fate

Genome architecture and stability in the Saccharomyces cerevisiae knockout collection

Long noncoding RNAs are involved in multiple immunological pathways in response to vaccination

Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells

Disease modelling in human organoids

The role of integrins in Drosophila egg chamber morphogenesis

Tracing the cellular dynamics of sebaceous gland development in normal and perturbed states

Neural stem cell dynamics: the development of brain tumours

Liver organoids: from basic research to therapeutic applications

NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs

 

Link to full list on PubMed