Microscopy image of Drosophila central brain (red and blue) and eye imaginal disc (green and red).

The developing visual system. The Drosophila central brain (red and blue) and eye imaginal disc (green and red) with dividing cells labelled in white (Jelle van den Ameele and Andrea Brand).

Our research

Within our remit to study development and disease, groups at the Institute work on a diverse range of research areas. We also use several different model organisms and apply up-to-the-minute techniques in genetics, gene editing, organoids, imaging and computational analysis.

Actin comets within a cell Gallop

Our research areas

Find out about our range of research areas and which group leaders work in each area.

Our impact

Our scientists publish 80+ papers each year in the top journals, many of which become highly cited as seminal findings in their field.

Our focus is fundamental biology, yet more than a dozen start-up companies have emerged from research at the Institute.  Several new therapies are now being tested in clinical trials, including for myeloid leukemia.

The cancer drug Olaparib resulted from Steve Jackson’s research on DNA damage repair and is now licensed for use around the world, prolonging the lives of people with ovarian, breast and prostate cancer.

Eric Miska and Tony Kouzarides with awards for STORM therapeutics

Scientific facilities

We boast many facilities available to our researchers, along with expert core staff to support learning and use of equipment, especially for imaging. We also offer next-generation sequencing on site, a core bioinformatics service and a high-performance compute cluster.

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