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Work-life balance: the bench and the barre

Andrea Brand features in the Academy of Medical Sciences campaign to encourage scientists to embrace and be open about their life outside of work. The #MedSciLife project celebrates the creativity, resilience and fresh perspectives that are nourished by outside interests and that build skills for doing quality research. Andrea's passion away from the bench is ballet.

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Probing pathways in Xist-mediated gene silencing

In this Nature Structural & Molecular Biology article, the Surani lab jointly with Edith Heard's Institut Curie lab examine the early development of female mouse embryos that lack Xist. This long non-coding RNA is an epigenetic regulator of gene expression by the X chromosome. Xist mutants show major perturbations in developmental pathways and die soon after implantation.

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Stem cell behaviour in mammary duct morphogenesis

The Simons lab, with colleagues in Cambridge and the Netherlands, combine genetic-lineage tracing and whole-gland mapping to identify the location and number of mammary stem cells and define quantitatively how the fate of these cells translates into organ structure.

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Front cover splash for Gurdon Institute research

This fabulous image from the Piddini lab's research on cell competition using the Drosophila gut as a model, by former lab member Saskia Suijkerbuijk, is on the cover of the new programme for this year's Cambridge Science Festival (13-26 March). The Gurdon Institute will be running a hands-on event on 18th March and taking part in two panel discussions and a film seminar - come and meet us there!

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Newly released video: Meet Andrea Brand

Andrea describes her research on neural stem cells in the final instalment of our series of ten group leader videos.

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Lynparza trial shows efficacy against breast cancer

Lynparza (olaparib), the anti-cancer drug that arose from Steve Jackson's research into DNA repair, became a registered medicine for some ovarian cancers in late 2014. AstraZeneca has now reported significant positive results from a Phase III clinical trial that may pave the way for Lynparza to be prescribed in certain breast cancer cases with BRCA1/2 mutations.

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Next in the Gurdon Institute Seminar Series

Coming up on Tuesday 28th February 2017, we welcome Irene Miguel-Aliaga (MRC London Institute of Medical Sciences) with her talk on ’Sex differences in organ size and plasticity’. All welcome.

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Studying development to understand disease

The Gurdon Institute is funded by the Wellcome Trust and Cancer Research UK to study the biology of development, and how normal growth and maintenance go wrong in cancer and other diseases.

 

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