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Meri Huch wins Hamdan Award for Medical Research Excellence

Gurdon Institute Group Leader Meri Huch has just been announced as one of the winners of the Sheikh Hamdan bin Rashid al Maktoum Awards for Medical Sciences, 2015-2016. Her prize will be presented at a ceremony in Dubai, United Arab Emirates, in December, and is for her "innovative methods and research" on liver disorders.

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New synthetic-lethal pair in the DNA damage response

Exploring the role of recently discovered PAXX, a factor in the cellular pathway that repairs DNA double-strand breaks, the Jackson group and colleagues show that loss of PAXX in combination with loss of XLF in mice is a lethal combination despite the mild health effects that result from loss of either factor alone.

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Early body axis patterning events under the microscope

In teasing out the early events underlying anterior-posterior axis formation in the fruit fly, the St Johnston lab and collaborators at Princeton tracked movements of bicoid mRNA with super-resolution and live microscopy. The mRNA moves by random active transport and becomes anchored to the anterior of the cell.

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Chromatin domains separate genes with different functions

By analysing patterns in the large-scale structure of chromatin, made up of DNA folded around histone proteins, the Ahringer lab find that different chromatin domains separate genes involved in development from those that are broadly expressed, and that the domains are subject to different kinds of regulation.

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MRC Senior Non-Clinical Fellowship for Emma Rawlins

Group Leader Emma Rawlins’ new 7-year funding award from the Medical Research Council supports her research on 'Cellular and molecular control of human embryonic alveolar development: towards lung regeneration’, and it will also enable her to recruit two additional post docs.

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Ahringer lab paper in inaugural issue of Wellcome Open Research

The Ahringer lab's paper, 'SeqPlots - interactive software for exploratory data analyses, pattern discovery and visualization in genomics', is among the first set of submissions to a new Open Science platform for Wellcome Trust funded research. The papers are published as open access before, during and after the peer review process.

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Meet our Group Leaders and hear about their research

You can find out about Gurdon Institute research 'from the horses' mouths' in our Meet the Group Leader videos on the Institute's YouTube channel. Tony, Emma, Eric and Steve describe their work on chromatin, lung development, non-coding RNA and the DNA damage response, respectively.

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Studying development to understand disease

The Gurdon Institute is funded by the Wellcome Trust and Cancer Research UK to study the biology of development, and how normal growth and maintenance go wrong in cancer and other diseases.