Latest mitochondria

Mitoballs
Publication - Ma

Mitoballs, large mitochondrial clusters, form to sustain sperm development

Dynamic mitochondria in spermatogenesis

August 14, 2023

Read more
A layer of Drosophila cells with nucleus marked red and mitochondria marked green. Image Klunicka et al, Ma Lab.
Publication - Ma

Identifying the molecular machinery for mitochondrial genome maintenance

REC repairs mitochondrial DNA by homologous recombination

November 10, 2022

Read more
Gonads undergoing sex determination. Image: Geraldine Jowett, Surani lab

Surani

1984, not the story you think

May 15, 2024

Fly vials in St Johnston lab

St Johnston

Spectraplakin binds a specific type of actin during oocyte fate formation

April 2, 2024

A specimen illuminated by fluorescent light on microscope stage in St Johnston lab

St Johnston

Implementation of a two-mirror scanning system enables fast volumetric imaging with a tilted light-sheet produced by a single objective on a fully functional commercial microscope base

March 15, 2024

Simons

Self-tuning of plasma cell lifespan by competition controls humoral immune memory

March 5, 2024

Germinal vesicles dissected from Xenopus meiotic oocytes containing potent factors to reprogram somatic cell nuclei.

Publication

Unlocking the potential for clinical application of reprogrammed somatic cells by germinal vesicles from Xenopus meiotic oocytes

March 1, 2024

Surani Lab - Freddy Wong at microscope and green screen

Surani

A groundbreaking method to study human neurodevelopment and disease

February 26, 2024

Fluorescence micrographs of frog growth cones before and after treatment with Cdc42 inhibitor, CASIN, showing membrane marker colour-coded by time.

Publication

TOCA-1 drives filopodial protrusion during neuronal development

February 7, 2024

Professor Ron Laskey

Three cheers for Prof Ron Laskey

February 6, 2024

Human primordial germ cell-like cells (yellow) co-cultured with human hindgut organoids (magenta/cyan).

Surani

Human primordial germ cell-like cells develop in human hindgut organoids

February 1, 2024

Ben Simons in his lab at the Gurdon Institute

Simons

Gurdon Institute welcomes new Director

January 2, 2024

Rendered image of cell lineage tracing in the stomach

Simons

Ben Simons awarded grand prix Charles-Léopold Mayer 2023 by the French Académie des Sciences

November 21, 2023

Human primordial germ cells in developing gonads

Surani

Advances in the in vitro derivation of human gametes bring hopes, but raises questions

November 14, 2023

Rawlins

Surani

Does scientific research on human embryos remain in line with society’s aspirations and social values? 

October 25, 2023

TOCA 1 filopodia

Publication

A new review of filopodia research

October 19, 2023

Ma Lab - Research at bench

News

Hansong Ma moves lab to Birmingham

October 11, 2023

Neonatal cerebellum

News

Sumru Bayin receives Wellcome Career Development Award

October 4, 2023

Lowe Syndrome Research Meeting 2023 group photo

News

Meet the Lowe Syndrome family

September 25, 2023

Advanced human primordial germ cell like cells induced in vitro by DMRT1/SOX17 colonized in mouse embryonic testicular organoids

Surani

A unique role for DMRT1 in the onset of human gametogenesis

September 14, 2023

Mitoballs

Publication

Mitoballs, large mitochondrial clusters, form to sustain sperm development

August 14, 2023

Steve Jackson

News

Steve Jackson awarded a knighthood for his services to innovation and research

June 17, 2023

Cross-section of a chicken embryo body axis

Xiong

Environmental forces control embryonic development

June 5, 2023

Human foetal lung stained to show epithelial cell outlines.

Rawlins

Control of cell shape in the developing human lung epithelium

May 23, 2023

Microinjector on microscope stage from Surani lab

Surani

Tracing the origin and segregation of the human germline

May 22, 2023

Xiong

A new method for measuring and exerting forces on the developing chicken embryo

May 1, 2023

Anne McLaren colour portrait

Remembering Anne McLaren

March 20, 2023

16 weeks post-conception human fetal lung. The branching airway tree is surrounded by bands of developing smooth muscle (green), which also labels the developing vasculature. The epithelial progenitor cells (co expressing SFTPC in white and NOTUM in red) are initiating the process of alveolar epithelial development. Image supplied by co-author Emma Rawlins (University of Cambridge), image credit Dr Kyungtae Lim.

Rawlins

Biggest leap in identified lung health genes paves way for personalised risk score

March 13, 2023

A 3D reconstructed tree of a murine salivary gland lobe showing clones resulting from labelling of individual progenitors that were traced from an early to a final stage of branching morphogenesis.

Simons

Tracing lineage restriction and patterning during branching morphogenesis

January 23, 2023

Immunostaining of a human female genital ridge in the 8th week of embryonic development depicting levels of H3K4me1 (red) and POU5F1 (green) in gonadal somatic cells and primordial germ cells (PGCs). Note that POU5F1-positive PGCs exhibit higher H3K4me1 levels than the surrounding somatic cells.

Surani

Human germline rejuvenation entails heterochromatin remodelling

January 18, 2023

Human primordial germ cell-like cells (yellow) co-cultured with human hindgut organoids (magenta/cyan).

Surani

Human primordial germ cell-like cell development in hindgut organoids

January 5, 2023

C. elegans adult germline expressing a GFP construct. The specific expression of the construct was driven by a TE-co-opted promoter.

Publication

Transposable elements recruited as promoters in the Caenorhabditis germline

December 16, 2022

Rawlins group_Human fetal lung tissue staining image showing alveolar development

Rawlins

Novel human lung organoids to study development and disease

December 8, 2022

Rawlins group_Human fetal lung tissue staining image describing a signalling niche for airway development

Rawlins

Human fetal lung cell atlas released

December 8, 2022

A layer of Drosophila cells with nucleus marked red and mitochondria marked green. Image Klunicka et al, Ma Lab.

Publication

Identifying the molecular machinery for mitochondrial genome maintenance

November 10, 2022

Microscopy image of human fetal lung explant shows birfurcating tips (red) and airway smooth muscle actin (cyan); by John Russell (Rawlins lab)

Rawlins

Rawlins lab shares in £8 million award for lung research

October 10, 2022

The simple layer of epithelial cells in the fruit fly midgut, with intestinal stem cells (ISC, smaller cells) situating at the basal side. Nuclear in cyan, alpha-Spectrin (cell cortical region) in magenta, and occluding septate junction in yellow.

St Johnston

How polarised epithelial cells grow “up” without breaking the barrier

September 28, 2022

Archival files on shelf in the admin office

Korean visitors come to learn about Institute’s core funding model

September 23, 2022

Kyungtae Lim in the Rawlins lab working at the tissue culture cabinet

Jackson

Publication

Rawlins

Identifying SOX9 as major regulator of lung progenitor self-renewal

September 19, 2022

Coloured tube holders in Tchasovnikarova lab

Tchasovnikarova

Identifying chromatin repressors and their roles in disease

September 16, 2022

Human developing lung section under microscope

Rawlins

Engaging the public with fundamental biology

September 15, 2022

Special tools for epithelioid culture in the Fernandez-Antoran lab

News

Growing epithelioids to reveal the mechanisms behind cell competition

September 14, 2022

Regenerating cerebellar cells identified by lineage tracing

News

Can we regulate stem cell behaviours to repair the brain?

September 12, 2022

Pipetting liquid with purple gloved hand in the Brand lab

Publication

Cph regulates neural stem cell temporal patterning

September 7, 2022

Twin chick embryo in development

Xiong

Watching mechanical forces shape the embryo

September 5, 2022

Chromosomes on computer screen in Jackson lab

News

Steve Jackson moves lab to CRUK Cambridge Institute

August 26, 2022

John Gurdon talks to Mary Archer and Tony Kouzarides

News

John Gurdon elected Fellow of the Science Museum Group

July 25, 2022

Simons

Brain tumours re-acquire developmental-like cell lineages

July 19, 2022

Rendered image of cell lineage tracing in the stomach

Simons

Retrograde movement sustains intestinal stem-cell numbers

July 13, 2022

BRCA1 mutant cell chromosomes Jackson

News

2022 Johann Anton Merck Award for Steve Jackson

July 12, 2022

Microinjector setup in Surani lab

Surani

Roadmap to guide in vitro gonadogenesis

July 6, 2022

Photo of drawer full of metal microscope components

St Johnston

Optimising spinning disk microscopy for imaging with PAINT

June 7, 2022

Fruit fly brain imaged with NanoDam technique fluorescent markers

Publication

NanoDam finds missing temporal factors

May 9, 2022

Researcher in darkened room looking donw microscope (Donovan A in Brand lab)

Publication

Deciphering Notch’s targets and mechanism

April 25, 2022

Surani lab microinjection rig

Surani

Untangling the mechanism of human primordial germ cell specification

April 11, 2022

Human Primordial Germ Cells visualised under microscope

Surani

Surani and single-cell sequencing

March 30, 2022

Lung organoids visualised under microscope

Rawlins

Emma Rawlins wins Tickle medal

February 25, 2022

Microinjector on microscope stage from Surani lab

Surani

Azim Surani wins Mendel Medal 2022

January 27, 2022

Frog eggs suspended in drop of water from Gallop lab

Publication

Active genes hold on to their transcription machinery

January 24, 2022

View of window past pipettes on shelf in the Tchasovnikarova lab

Tchasovnikarova

Reporter cell lines for epigenetic pathways

January 20, 2022

Worm plates in the Ahringer lab

Publication

New tool to study genome topology and regulatory interactions

December 21, 2021

Yeast colonies growing on a screening plate

News

ASPIRE Award for Jackson projects

December 17, 2021

St Johnston

Unexpected clustering of nuclear pores revealed by new tissue imaging system

December 16, 2021

Eppendorf tubes in a red block on bench

Publication

Detecting RNA modifications

December 10, 2021

Fly vials in St Johnston lab

St Johnston

Polarity axes in Drosophila

December 1, 2021

Poster illustration for E Robertson seminar

Anne McLaren Lecture 2021

November 12, 2021

Researcher with gloved hands reaches into open incubator with petri dishes in Miska Lab

Publication

Transposon activity shapes fungal evolution

November 12, 2021

Fly sorting in St Johnston lab

St Johnston

Breaking symmetry to establish oocyte identity

November 11, 2021

Drosophila under blue scope light

Publication

Fat flies – a slimmed down model of human obesity

November 8, 2021

Steve Jackson standing in the garden of Gurdon Institute

News

Man on a Mission

November 1, 2021

Ahringer lab flask incubator

Publication

DREAM functions are mediated by THAP proteins

October 19, 2021

Surani lab microinjection rig

Surani

Tracing the origin of PGCs in rabbit

October 12, 2021

Tube rotator Kouzarides lab

Publication

Genetics of female reproductive longevity

August 4, 2021

Front view of Gurdon Institute

News

Simons

Two new Fellows of the Royal Society

May 6, 2021